Details
Quality products?make an important contribution to long-term revenue and profitability. Factory Sells Best Quality 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline 42835-89-2 with USP
1.What is the 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline ?
Intermediate in the production of anti-cancer quinoline derivatives and antibacterial agents
-
-
1128-61-6
6-fluoro-2-methyl-quinoline
-
-
42835-89-2
6-fluoro-1,2,3,4-tetrahydro-2-methylquinoline
| Conditions | Yield |
|---|---|
|
With
diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;
In
dichloromethane;
at 25 ℃;
for 96h;
|
98%
|
|
With
diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; tetramethyl 5-(hydroxy(methoxy)methylene)cyclopenta-1,3-diene-1,2,3,4-tetracarboxylate;
In
chloroform;
at 20 ℃;
for 2h;
|
98%
|
|
With
platinum on carbon; hydrogen; acetic acid;
at 20 ℃;
for 16h;
under 23272.3 Torr;
|
98%
|
|
With
formic acid; C29H32ClIrNO; sodium formate;
In
water;
at 30 ℃;
for 14h;
pH=4.5;
|
97%
|
|
With
C46H49CoN3P4(2+)*2BF4(1-); hydrogen; potassium hydroxide;
In
toluene; acetonitrile;
at 100 ℃;
for 48h;
under 22801.5 Torr;
chemoselective reaction;
Autoclave;
Glovebox;
|
96%
|
|
With
aluminum (III) chloride; tricarbonylcyclopentadienyltungsten(II) chloride; hydrogen;
In
isopropyl alcohol;
at 120 ℃;
for 14h;
under 37503.8 Torr;
|
96%
|
|
With
hydrogen;
In
toluene;
at 120 ℃;
for 24h;
under 3750.38 Torr;
Autoclave;
|
95%
|
|
With
hydrogen;
In
water; isopropyl alcohol;
at 130 ℃;
for 66h;
under 37503.8 Torr;
Reagent/catalyst;
chemoselective reaction;
|
94%
|
|
With
hydrogen;
In
toluene;
at 80 ℃;
for 24h;
under 30003 Torr;
chemoselective reaction;
|
94%
|
|
With
hydrogen;
In
water; isopropyl alcohol;
at 70 ℃;
for 24h;
under 7500.75 Torr;
Autoclave;
|
92%
|
|
With
cobalt(II) tetrafluoroborate hexahydrate; tris(2-diphenylphosphinophenyl)phosphine; hydrogen;
In
tetrahydrofuran;
at 60 ℃;
for 15h;
under 7500.75 Torr;
chemoselective reaction;
Autoclave;
|
91%
|
|
With
hydrogen; cobalt(II) diacetate tetrahydrate; zinc;
In
water;
at 100 ℃;
for 15h;
under 22502.3 Torr;
Sealed tube;
Autoclave;
|
91%
|
|
With
hydrogen; iodine;
[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2;
In
tetrahydrofuran;
at 20 ℃;
for 12h;
under 31029.7 Torr;
|
90%
|
|
With
diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; boric acid;
In
1,2-dichloro-ethane;
at 60 ℃;
for 7h;
chemoselective reaction;
|
89%
|
|
With
diphenyl hydrogen phosphate; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;
In
benzene;
at 60 ℃;
for 12h;
|
88%
|
|
With
hydrogen;
In
toluene;
at 100 ℃;
for 6h;
under 1125.11 - 6000.6 Torr;
Autoclave;
|
88%
|
|
With
hydrogen;
In
toluene;
at 120 ℃;
for 18h;
under 9000.9 Torr;
regioselective reaction;
Autoclave;
Sealed tube;
|
83%
|
|
With
ethanol; Dimethylphenylsilane; Au-TiO2;
In
neat (no solvent);
at 70 ℃;
for 0.333333h;
|
82%
|
|
With
hydrogenchloride; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; isopropyl alcohol;
In
water; 1,2-dichloro-ethane;
for 24h;
Inert atmosphere;
Sealed tube;
Irradiation;
Heating;
|
75%
|
|
With
dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; potassium iodide;
at 40 ℃;
for 12h;
|
74%
|
|
With
rhodium; hydrogen; 1-butyl-3-methylimidazolium Tetrafluoroborate;
at 120 ℃;
for 48h;
under 22502.3 Torr;
chemoselective reaction;
Autoclave;
|
73%
|
|
With
6C53H32O8(4-)*13Zr(4+)*18O(2-)*8Co(2+)*8Cl(1-); hydrogen; sodium triethylborohydride;
In
toluene;
at 80 ℃;
for 48h;
under 30003 Torr;
|
72%
|
|
With
ethanol; sodium;
at 20 - 50 ℃;
|
68%
|
|
With
diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; C38H52N4S2(2+)*2CF3O3S(1-);
In
chloroform-d1;
at 20 ℃;
for 12h;
Sealed tube;
|
57%
|
|
With
iodine; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane;
In
toluene;
at 100 ℃;
Inert atmosphere;
|
44%
|
|
With
C26H26ClN2O2RhS; sodium formate; sodium acetate; acetic acid;
In
water;
at 40 ℃;
pH=5;
Sealed tube;
|
|
|
With
6C53H32O8(4-)*13Zr(4+)*18O(2-)*8Co(2+)*8H(1-); hydrogen;
In
tetrahydrofuran;
at 80 ℃;
for 48h;
under 30003 Torr;
|
72 %Spectr.
|
|
With
diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; C18H18N2O2S3;
In
dichloromethane-d2;
at 20 ℃;
Inert atmosphere;
|
|
|
With
diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; C30H26N4O4S2Se2;
In
dichloromethane-d2;
at 20 ℃;
for 48h;
|
88 %Spectr.
|
-
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123-73-9,4170-30-3
trans-Crotonaldehyde
-
-
371-40-4
4-fluoroaniline
-
-
42835-89-2
6-fluoro-1,2,3,4-tetrahydro-2-methylquinoline
| Conditions | Yield |
|---|---|
|
With
ammonium acetate;
platinum;
In
hydrogenchloride; methanol; water; acetic acid; isopropyl alcohol; acetone; toluene;
|
|
|
With
ammonium acetate;
platinum;
In
hydrogenchloride; methanol; water; acetic acid; isopropyl alcohol; acetone; toluene;
|
2.What is the CAS number for 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline ?
The CAS number of 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline is 42835-89-2.
More information of 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline 42835-89-2 are:
|
CAS?Number |
42835-89-2 |
|
Density |
1.056 g/cm3 |
|
Melting Point |
31-33 °C |
|
Boiling Point |
254.6 °C at 760 mmHg |
|
Flash Point |
107.8 °C |
|
HS CODE |
2933499090 |
|
PSA |
12.03000 |
|
LogP |
2.71030 |
|
Pka |
5.21±0.40(Predicted) |
3.What are another words for 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline ?
Synonyms?for?6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline 42835-89-2:1,2,3,4-Tetrahydro-6-fluoro-2-methylquinoline;6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline;
4.What is the molecular formula of 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline?
The chemical formula of ?6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline is?C10H12FN which containing 10 Carbon atoms,12 Hydrogen atoms,1 Fluorine atoms and 1 Nitrogen atoms,and the molecular weight of??6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline?is 165.21.
5.What is 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline (42835-89-2) used for?
6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline is a white to yellowish crystalline low melting solid that serves as an intermediate in the production of anti-cancer quinoline derivatives and antibacterial agents. Its chemical structure and properties make it a valuable compound in the pharmaceutical industry.
InChI:InChI=1/C10H12FN/c1-7-2-3-8-6-9(11)4-5-10(8)12-7/h4-7,12H,2-3H2,1H3
Relevant articles related to 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline:
|
Article |
Source |
|
Heterogeneous Hydrogenation of Quinoline Derivatives Effected by a Granular Cobalt Catalyst |
Timelthaler, Daniel,Topf, Christoph , (2021/11/22) |
|
Reductive Alkylation of Quinolines to N-Alkyl Tetrahydroquinolines Catalyzed by Arylboronic Acid |
Adhikari, Priyanka,Bhattacharyya, Dipanjan,Nandi, Sekhar,Kancharla, Pavan K.,Das, Animesh supporting information, p. 2437 - 2442 (2021/04/05) |
6.Buy 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline with the best price .
Qinhuangdao Suke Chemical Product Co.,Ltd is a quality supplier of 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline 42835-89-2.
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