4-Chloro-3-fluoroaniline

  • CAS:367-22-6
  • purity:99%
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1.What is the 4-Chloro-3-fluoroaniline ?

White to light yellow solid

4-Chloro-3-fluoroaniline is an organic compound characterized by its white to light yellow solid appearance. It is a derivative of aniline, with a chlorine atom at the 4th position and a fluorine atom at the 3rd position, which imparts unique chemical properties to the molecule.

2.What is the CAS number for 4-Chloro-3-fluoroaniline ?

The CAS number of 4-Chloro-3-fluoroaniline is 367-22-6.

3.What are another words for 4-Chloro-3-fluoroaniline ?

Synonyms?for?4-Chloro-3-fluoroaniline 367-22-6:4-Chloro-3-fluoro-phenylamine;3-Fluoro-4-chloroaniline;

4.What is 4-Chloro-3-fluoroaniline (367-22-6) used for?

4-Chloro-3-fluoroaniline is used in the synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate; a key intermediate towards phosphoindole inhibitors of HIV non-nucleoside reverse transcriptase. 4-Chloro-3-fluoroaniline is also used in the synthesis of 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib (D289540) which is an impurity of the tyrosine kinase inhibitor Gefitinib.

InChI:InChI=1/C6H5ClFN/c7-5-2-1-4(9)3-6(5)8/h1-3H,9H2

Relevant articles related to 4-Chloro-3-fluoroaniline:

Article

Source

Catalyst-Controlled Regioselective Chlorination of Phenols and Anilines through a Lewis Basic Selenoether Catalyst

Dinh, Andrew N.,Maddox, Sean M.,Vaidya, Sagar D.,Saputra, Mirza A.,Nalbandian, Christopher J.,Gustafson, Jeffrey L.

, p. 13895 - 13905 (2020/11/03)

CD4 mimics as HIV entry inhibitors: Lead optimization studies of the aromatic substituents

Narumi, Tetsuo,Arai, Hiroshi,Yoshimura, Kazuhisa,Harada, Shigeyoshi,Hirota, Yuki,Ohashi, Nami,Hashimoto, Chie,Nomura, Wataru,Matsushita, Shuzo,Tamamura, Hirokazu

, p. 2518 - 2526 (2013/06/26)

Copper(I)-catalyzed amination of aryl halides in liquid ammonia

Ji, Pengju,Atherton, John H.,Page, Michael I.

, p. 7471 - 7478 (2012/11/06)

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