1,6-dihydro-4-hydroxy-2-methyl-6-oxonicotinonitrile

  • CAS：64169-92-2
  • purity：99%
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Details

Quality Factory Sells Top Purity 99% 1,6-dihydro-4-hydroxy-2-methyl-6-oxonicotinonitrile 64169-92-2 with Safe Delivery

  • Molecular Formula: C7H6 N2 O2
  • Molecular Weight: 150.137
  • Vapor Pressure: 0.000121mmHg at 25°C 
  • Boiling Point: 299.2ºC at 760 mmHg 
  • Flash Point: 134.8ºC 
  • PSA： 76.88000 
  • Density: 1.38g/cm3 
  • LogP: 0.26058 

1,6-dihydro-4-hydroxy-2-methyl-6-oxonicotinonitrile(Cas 64169-92-2) Usage

General Description

1,6-dihydro-4-hydroxy-2-methyl-6-oxonicotinonitrile is a chemical compound with the molecular formula C7H9N3O2. It is a derivative of nicotinic acid and is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 1,6-dihydro-4-hydroxy-2-methyl-6-oxonicotinonitrile has a six-membered ring with a hydroxyl group and a nitrile group attached to it, and a methyl group attached to the second carbon. It is a white to beige solid that is soluble in water and other polar solvents. This chemical is mainly used in the synthesis of various drugs and is also used as a building block in the preparation of bioactive molecules. Additionally, it has shown potential as an antifungal agent in agricultural applications.

InChI:InChI=1/C7H6N2O2/c1-4-5(3-8)6(10)2-7(11)9-4/h2H,1H3,(H2,9,10,11)

64169-92-2 Relevant articles

INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS

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Page/Page column 408; 409, (2021/01/29)

The present invention is directed to ind...

SUBSTITUTED BICYCLE HETEROCYCLIC DERIVATIVES USEFUL AS ROMK CHANNEL INHIBITORS

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Page/Page column 152; 153, (2018/06/06)

Disclosed are compounds of Formula (I) o...

NOVEL COMPOUNDS THAT ARE ERK INHIBITORS

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Page/Page column 146, (2014/04/17)

Disclosed are the ERK inhibitors of form...

Synthesis and biological evaluation of C-5 methyl substituted 4-arylthio and 4-aryloxy-3-iodopyridin-2(1H)-one type anti-HIV agents

Guillemont, Jér?me,Benjahad, Abdellah,Oumouch, Said,Decrane, Laurence,Palandjian, Patrice,Vernier, Daniel,Queguiner, Laurence,Andries, Koen,De Béthune, Marie-Pierre,Hertogs, Kurt,Grierson, David S.,Nguyen, Chi Hung

scheme or table, p. 7473 - 7487 (2010/06/11)

A series of C-5 methyl substituted 4-ary...

64169-92-2 Process route

malonic acid bis-(2,4,6-trichloro-phenyl) ester
15781-70-1

malonic acid bis-(2,4,6-trichloro-phenyl) ester

(E/Z)-3-aminoprop-2-enenitrile
19866-98-9

(E/Z)-3-aminoprop-2-enenitrile

4-hydroxy-2-methyl-6-oxo-1,6-dihydropyridine-3-carbonitrile
64169-92-2

4-hydroxy-2-methyl-6-oxo-1,6-dihydropyridine-3-carbonitrile

Conditions
Conditions Yield
With diethylene glycol dimethyl ether; at 120 ℃; for 2.5h;
59.7%
3-Aminocrotononitrile
1118-61-2

3-Aminocrotononitrile

malonic acid bis-(2,4,6-trichloro-phenyl) ester
15781-70-1

malonic acid bis-(2,4,6-trichloro-phenyl) ester

4-hydroxy-2-methyl-6-oxo-1,6-dihydropyridine-3-carbonitrile
64169-92-2

4-hydroxy-2-methyl-6-oxo-1,6-dihydropyridine-3-carbonitrile

Conditions
Conditions Yield
In diethylene glycol dimethyl ether; at 120 ℃; for 2h;
In chlorobenzene; at 130 ℃; for 3h;
540 mg

64169-92-2 Upstream products

  • 1118-61-2
    1118-61-2

    3-Aminocrotononitrile

  • 15781-70-1
    15781-70-1

    malonic acid bis-(2,4,6-trichloro-phenyl) ester

  • 763-33-7
    763-33-7

    (E)-3-aminocrotononitrile

  • 19866-98-9
    19866-98-9

    (E/Z)-3-aminoprop-2-enenitrile

64169-92-2 Downstream products

  • 1185190-81-1
    1185190-81-1

    4,6-dichloro-2-methyl-3-cyanopyridine

  • 1589541-04-7
    1589541-04-7

    (R)-(4-chloro-3-cyano-6-(3-(1-phenylethyl)ureido)pyridin-2-yl)methyl acetate

  • 1589536-75-3
    1589536-75-3

    (R)-1-(3-amino-4-(hydroxymethyl)-1H-pyrazolo[4,3-c]pyridin-6-yl)-3-(1-phenylethyl)urea

  • 1589541-06-9
    1589541-06-9

    (R)-1-(4-chloro-5-cyano-6-(methoxymethyl)pyridin-2-yl)-3-(1-phenylethyl)urea

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